By Leonard C. Sperling
Diagnosing and treating hair issues is an integral part of either scientific and beauty dermatology perform. due to the fact that it is a topic that's infrequently or in simple terms superficially coated in the course of residency education, the pathologists and dermatopathologists who needs to assessment specimens submitted with a medical analysis of hair sickness usually discover a hole of their wisdom. The filing dermatologist often needs to act as pathologist in addition to clinician. greater than only a ebook on hair affliction, An Atlas of Hair Pathology with scientific Correlations bridges that hole. the 1st entire evaluation of the microscopic pathology of hair disorder, this e-book serves as a primer, an atlas, and a reference. As a primer, it experiences very easy info, together with hair anatomy and the "nuts and bolts" of processing and comparing specimens. As an atlas, it truly is wealthy in images demonstrating uncomplicated and complicated histologic beneficial properties of hair ailment. And, as a reference, it comprises up to date info and a evaluation of uncomplicated medical good points that supply a clinical-pathologic correlation. With 365 illustrations from the author's own choice of slides, An Atlas of Hair Pathology with medical Correlations is the main entire and "user-friendly" source on hair pathology on hand.
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Additional resources for An Atlas of Hair Pathology with Clinical Correlations (The Encyclopedia of Visual Medicine Series)
8. Note: as mentioned earlier, the diagnostic significance of catagen and telogen hairs is the same, since all catagen hairs become telogen hairs within a few weeks. Therefore, follicles in either of these two phases can be referred to as catagen/telogen hairs. 11 In this example of lichen planopilaris, lymphocytic inflammation is concentrated around the upper half of the follicle. Vacuolar, basilar degeneration is present. 12 In this example of central, centrifugal scarring alopecia, chronic inflammation is concentrated at the level of the isthmus and lower infundibulum.
Yet another but more tedious method involves embedding the epidermal and/or fat end down in the cassette, and taking multiple horizontal sections through the entire specimen. Dozens of sections can be required to section through the entire block, and the block is exhausted in the process. However, every possible level of every follicle in the specimen can be carefully studied, and this technique is useful for research purposes. BIBLIOGRAPHY Frishberg DP,Sperling LC,GuthrieVM. Transverse scalp sections: a proposed method for laboratory processing.
To assist in this process, some especially important histological features (listed below) will help to segregate the diagnostic entities. Identifying additional histological features will make it easier to establish the diagnosis. Frequently, different diseases may share two or more histological features. When this occurs, separating such diseases may rest on good clinical correlation or subtle histological clues. Attempts have been made to create ‘alopecia algorithms’ for arriving at a diagnosis, but in the author’s experience, such algorithms provide little assistance.